Where are you from? Naming a childhood town is an easy reply for many,
but for an adopted child or young refugees separated from their parents,
the answer may never come. Now, a new app could help those who are
unaware of their ancestral home. Using only DNA sequences, the program
can trace how far away a person lives from the land of their forebears,
according to a study published today inNature Communications. The system
relies on admixture—a genetic principle that argues that when a family
migrates across a geographic barrier into a new location, they start
mating with the locals; new traits start blending into their gene pool,
and this genetic diversity provides a ruler for gauging the distance
from home. The researchers started with a genome database of people from
54 worldwide regions (dots in map above). The subjects had historic
ties to their regions dating back centuries. Using this info, the team
built an admixture algorithm, dubbed Geographic Population
Structure(GPS), which they tested with the genetic info from 600 DNA
samples composed of 98 global subpopulations, such as Romanians or the
Punjabis of northern India. Based solely on genetic markers, GPS could
place individuals within their country of origin 83% of the time. Half
of the subjects were pinpointed within 87 km of their reported point of
origin. For instance, all female subjects from the mountain commune of
San Basilio, Sardinia, were placed in their original village (inset).
But the biggest claim made by the study is that humans are a highly
mixed species with no evidence for races.
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